https://www.ceesdekker.net Secrets

https://www.ceesdekker.net Secrets

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Employing single-molecule optical and AFM imaging and force-spectroscopy procedures, we search for to unravel the mechanistic facets of the structure and dynamics of chromosomes. Our investigate passions contain:

Human Rad51 filaments on double- and single-stranded DNA: correlating common and irregular types with recombination purpose.

Multicolor imaging from the bacterial nucleoid and mobile division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins

Since 2000, Dekker has shifted the principle aim of his operate to biophysics exactly where he reports the Attributes of single biomolecules and cells using the equipment of nanotechnology. This alteration of field was driven by his fascination to the amazing performing of biological molecular structures, along with with the very long-time period perspective that a lot of appealing discoveries is usually expected Within this area.[5] Existing traces of investigation in his biophysics team are from the parts of:[six]

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Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

Size control of person carbon nanotubes by nanostructuring Using the scanning tunneling microscope

Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation

‘Of course, I comprehend persons were amazed at the time. At the end of the nineties, After i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t study A lot any more. The sphere went much more into the appliance facet, how you may combine nanotubes into Digital circuits.

There was a person dilemma while — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting cees dekker polymers were being actually not such fantastic conductors, which was instead disappointing. We Hence broadened our look at to try to discover far more promising molecules.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

1999, 1st measurement of the wavefunction of solitary molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive proof to get a new Luttinger description of interacting electrons in nanotubes

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It absolutely was an extremely interesting time, in the course of which I gained a lot of help from Delft College of Technological know-how, exactly where I used to be a professor at enough time, And that i begun a number of collaborations with molecular biologists. That assisted me study lots.’